Homozygous familial hypercholesterolaemia: new hope for getting patients to goal?

Management of homozygous familial hypercholesterolaemia is challenging. What are the prospects for attaining LDL cholesterol goal with novel therapies? This latest commentary discusses the new findings for evinacumab, an ANGPTL3 monoclonal antibody. The European Atherosclerosis Society (EAS) continues to be a key player in familial hypercholesterolaemia (FH), raising awareness and supporting research to promote early … Read more

HICC registry: levelling up access to treatment urgently needed

Commentary to publication: Worldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study. The Lancet; Familial hypercholesterolaemia (FH) is an inherited condition characterised by markedly elevated low-density lipoprotein cholesterol (LDL-C) levels from birth, which if undiagnosed and untreated, confer an increased risk of premature atherosclerotic cardiovascular disease. The most severe presentation is homozygous FH, estimated … Read more

FHSC new publication in The Lancet – highlighting the challenges of FH

September 07, 2021 – Gothenburg, Sweden First data from the European Atherosclerosis Society (EAS) Familial Hypercholesterolaemia Studies Collaboration (FHSC) global registry of over 42,000 individuals from 56 countries, provides a unique snapshot into the worldwide burden and challenges of FH care. Detection needs to be earlier, with greater use of intensive lipid-lowering therapy, including combination … Read more

Improving FH care: first survey data from EAS FHSC

2019-04-26 Five years ago, the European Atherosclerosis Society (EAS) was a trailblazer in highlighting the underdiagnosis and undertreatment of familial hypercholesterolaemia (FH, inherited high cholesterol) in a Consensus Panel initiative.1 This was followed by subsequent statements, specifically focusing on homozygous FH,2 and importantly, FH in children and adolescents.3 Supported by other international evidence,4-7 the EAS recognised the worldwide lack … Read more