FH related publications 2025

Cost-effectiveness of alternative cascade screening strategies for familial hypercholesterolemia with realistic cascade screening acceptance rates and use of novel treatment

• Jing Lou, Kok Joon Chong, Sharon Li Ting Pek, Yasmin Bylstra, Chester Lee Drum, Weng Khong Lim, Yi Wang, Khung Keong Yeo, Subramaniam Tavintharan, W.E.E. Hwee-Lin
• DOI: 10.1016/j.atherosclerosis.2025.120416
• Atherosclerosis, July 12, 2025 Open access

Risk of adverse pregnancy outcomes and impact of statin use in pregnant women with familial hypercholesterolemia

• Karianne Svendsena, Jacob Juel Christensen, Jannicke Igland, Henriette Walaas Krogh, Liv J. Mundala, David R. Jacobs, Martin P. Bogsrud, Kirsten B. Holven, Kjetil Retterstøl
• DOI: 10.1016/j.atherosclerosis.2025.120442
• Atherosclerosis Vol. 408, September 2025 Open access

Uncovering familial hypercholesterolaemia phenotype in the community: How primary care can transform early detection and management

• Ralph K. Akyea, Nadeem Qureshi
• DOI: 10.1016/j.atherosclerosis.2025.120427
• Atherosclerosis Vol. 408, September 2025 Open access

Protein-truncating variants of the cholesteryl ester transfer protein gene and risk for coronary artery disease among patients with heterozygous familial hypercholesterolemia

• Hayato Tadaa, Atsushi Furukawaa, Nobuko Kojimaa, Soichiro Usuia, Kenji Sakataa, Masa-aki Kawashirib, Masayuki Takamura
• DOI: 10.1016/j.atherosclerosis.2025.120417
• Atherosclerosis Vol. 408, September 2025 Open access

Sex differences in cholesterol levels among prepubertal children

• Jan Kafol, Mia Becker, Barbara Cugalj Kern, Jaka Sikonja, Matej Mlinaric, Katarina Sedej, Matej Kafol, Ana Drole Torkar, Jernej Kovac, Tadej Battelino, Urh Groselj
• DOI: 10.1016/j.atherosclerosis.2025.120484
• Atherosclerosis, August 17, 2025

Clinical profile of familial hypercholesterolemia phenotype in adults attended in primary care in a large healthcare area

• Teresa Gijón-Condea, José R. Banegas, Carolina Ferré Sánchezd, Rodrigo Alonso, Pedro Mataf
• DOI: 10.1016/j.atherosclerosis.2025.120400
• Atherosclerosis June 04, 2025

Evinacumab and reduced lipoprotein apheresis in pediatric homozygous familial hypercholesterolemia: a retrospective study on LDL-C

• Charlotte Nigmann, Manuela Neyer, Sophie Draxler-Dworzak, Margot Baumgartner-Kaut, Thomas Müller-Sacherer, Klaus Arbeiter, Susanne Greber-Platzer
• DOI: 10.1016/j.atherosclerosis.2025.119234
• Atherosclerosis Vol. 406, July 2025 Open access

Angiopoietin-like protein inhibitors: Promising agents for the treatment of familial hypercholesterolemia and atherogenic dyslipidemia

• Fatemeh Vahdat-Lasemi, Leila Farhoudi, Seyedeh Maryam Hosseinikhah, Raul D. Santos, Amirhossein Sahebkar
• DOI: 10.1016/j.atherosclerosis.2025.119235
• Atherosclerosis Vol. 405, June 2025

Homozygous familial hypercholesterolemia evaluation and survival single center study in Saudi Arabia: The HESSA registry

• Naji Kholaif, Lin Batha, Sumayah Aljenedil, Zuhier Ahmed Awan, Nadiah AlRuwaili, Abdulrahman Khalid Habib, Ahmed Awni Jouda, Maria Teresa Savo, Fadl Elmula M. Fadl Elmula, Tahir I. Mohamed, Abdullah Al-Ashwal, Valeria Pergola, Naser Elkum, Domenico Galzerano
• DOI: 10.1016/j.atherosclerosis.2025.119214
• Atherosclerosis Vol. 405, June 2025 Open access

Impact of the clinical diagnostic strata of familial hypercholesterolemia on risk stratification among patients with hypercholesterolemia

• Hayato Tada, Atsushi Nohara, Soichiro Usui, Kenji Sakata, Masa-aki Kawashiri, Masayuki Takamura
• DOI: 10.1016/j.atherosclerosis.2025.119185
• Atherosclerosis Vol. 404, May 2025 Open access

Real-world family planning and pregnancy practices in women with homozygous familial hypercholesterolemia

• Janneke W.C.M. Mulder, Willemijn A.M. Schonck, Tycho R. Trompc, M. Doortje Reijman, Laurens F. Reeskamp, G. Kees Hovingh, Dirk J. Blom, Jeanine E. Roeters van Lennep
• DOI: 10.1016/j.atherosclerosis.2025.119187
• Atherosclerosis Vol. 404, May 2025 Open access

Association of Achilles tendon thickness with lipid profile and carotid IMT in patients with familial hypercholesterolemia

• Masahito Michikuraa, Masatsune Ogura, Mika Hori, Kota Matsuki, Hisashi Makino, Shimpei Fujioka, Daisuke Shishikura, Masaaki Hoshiga, Mariko Harada-Shiba
• DOI: 10.1016/j.atherosclerosis.2025.119173
• Atherosclerosis Vol. 403, April 2025

Association between statin adherence and arterial stiffness in young adult patients with familial hypercholesterolemia: A cross-sectional study

• Sibbeliene E. van den Bosch, Barbara A. Hutten, Alma Revers, Eric M. Schrauben, Pim van Ooijc, Aart J. Nederveenc, Willemijn E. Corpeleijn, Albert Wiegman
• DOI: 10.1016/j.atherosclerosis.2025.119175
• Atherosclerosis Vol. 404, May 2025

Cardiovascular disease morbidity is associated with social deprivation in subjects with familial hypercholesterolaemia (FH): A retrospective cohort study of individuals with FH in UK primary care and the UK Simon Broome register, linked with national hospital records

• B. Iyen, N. Qureshi, J. Kai, N. Capps, P.N. Durrington, J. Cegla, H. Soran, J. Schofield, H.A.W. Neil, S.E. Humphries on behalf of the Simon Broome Familial Hyperlipidaemia Register Group 
• DOI: 10.1016/j.atherosclerosis.2025.119142
• Atherosclerosis Vol. 403, April 2025 Open access

Efficacy and safety of ongericimab in Chinese patients with heterozygous familial hypercholesterolemia: A randomized, double-blind, placebo-controlled phase 3 trial

• Jie Lin, Yuan Ji, Gaopin Wang, Xueping Ma, Zhuhua Yao, Xuebin Han, Jie Chen, Jiyan Chen, Wei Huang, Guangma Xu, Daoquan Peng, Peishi Yan, Ping Qiao, Yongming He, Yida Tang, Minghui Wang, Mengqi Zhang, Jianjun Yu, Yu Hao, Changsheng Ma
• DOI: 10.1016/j.atherosclerosis.2025.119120
• Atherosclerosis Vol. 403, April 2025 Open access

Targeting LDL aggregation decreases atherosclerotic lipid burden in a humanized mouse model of familial hypercholesterolemia: Crucial role of ApoB100 conformational stabilization

• A. Benitez-Amaro, E. Garcia, M.T. La Chica Lhoëst, A. Martínez, C. Borràs, M. Tondo, M.V. Céspedes, P. Caruana, A. Pepe, B. Bochicchio, A. Cenarro, F. Civeira, R. Prades, J.C. Escola-Gil, V. Llorente-Cortés
• DOI: 10.1016/j.atherosclerosis.2024.118630
• Atherosclerosis, October 19, 2024 Open access

Efficacy and safety of statins, ezetimibe and statins-ezetimibe therapies for children and adolescents with heterozygous familial hypercholesterolaemia: Systematic review, pairwise and network meta-analyses of randomised controlled trials

• Alexis Llewellyn, Mark Simmonds, David Marshall, Melissa Harden, Beth Woods, Steve E. Humphries, Uma Ramaswami, Lorraine Priestley-Barnham, Mark Fisher, Laila J. Tata, Nadeem Qureshi
• DOI: 10.1016/j.atherosclerosis.2024.118598
• Atherosclerosis, Vol. 401, February 2025 Open access

Cascade screening of a Pakistani consanguineous familial hypercholesterolemia cohort: Identification of seven new homozygous patients

• Quratul Ain, Jaka Sikonja,  Fouzia Sadiq, Saeed Shafi, Jan Kafol, Tevz Gorjanc, Ursa Sustar, Jernej Kovac, Mohammad Iqbal Khan, Muhammad Ajmal, Urh Groselj
• DOI: 10.1016/j.atherosclerosis.2025.119118
• Atherosclerosis, Vol. 402, March 2025 Open access